PO'ed is a first-person shooter using primitive weapons such as a frying pan and a drill, as well as futuristic alien weapons. The player must advance through 26 levels filled with alien monsters. A jet pack can also be acquired to facilitate the player's exploration of levels. When the jet pack is selected, the jump button instead causes the player character to accelerate skyward, and releasing the button causes the player character to fall, accelerating downwards. The physics-based jet pack thus does not allow the player character to naturally hover, though they can maintain a relatively steady altitude by rhythmically tapping the jet pack button.

A chef's spacecraft has crash-landed on an alien world, and he must escape.