The computer versions of Hard Rock Casino include blackjack, craps, keno, and poker. The mobile version starts the player off with $5,000, and includes three casino games: blackjack, poker, and a slot machine.

The PlayStation versions feature four casinos and 22 casino games, including slot machines, poker, blackjack, roulette, craps, baccarat, pai gow, Let It Ride and Casino War. The player is given body type and clothing options to create a customized player character. The game includes a story mode in which the player tries to win enough money to gamble at high roller casinos. To progress through the story mode, the player must play and win the various gambling games to advance from one casino to the next casino. The PSP version includes a wireless multiplayer option.